Archive of Harki Laboratory News

New Manuscript in Cell Chemical Biology

HLB-0532259 induces Aurora kinase A and N-Myc degradation.

Targeted degradation of Aurora kinase A results in degradation of N-Myc in pediatric neuroblastoma. See our work in Cell Chem. Biol. (pdf).

New publication in ACS Med Chem Lett

ACS MCL 2023 TOC - Anderson

Congratulations to Jared and Michael for their recent publication on the development of allosteric NIK-binding fragments in ACS Med Chem Lett (link).

New publication in ACS Med Chem Lett

A3A E72 Mutations

Congratulations to Katherine and our collaborators for their ACS Med. Chem. Lett. manuscript on APOBEC3A stability with mutations to the catalytic glutamic acid! [pdf]