• Harki laboratory research interests
  • The Harki Group 2018 (from left): Ram, Anand, Sam S., David, Henry, Sam, Kellan, Jian, Michael, Kat, and Dan. Not pictured: Sydney, Jordan, and Chris.

Lab Announcements

Congratulations to Chris Richards

Chris Richards

Congratulations to Dr. Chris Richards, a co-mentored graduate student with the Harris laboratory, for defending his Ph.D. in Pharmacology! Best wishes as a postdoctoral fellow in the Carette laboratory at Stanford University!

4CIN: A universal fluorescent nucleoside analogue

4CIN OL TOC Graphic

Our paper reporting the synthesis and characterization of 4CIN, a fluorescent nucleoside analogue containing a 4-cyanoindole nucleobase, is now available at Organic Letters.

 

Research Interests

Research in the Harki laboratory focuses on the design, synthesis and biological characterization of novel small molecules, peptides, and oligonucleotides that influence cellular function.

Applications for these molecules range from anticancer drug discovery to new tools for modern biotechnology research.

Our core science is organic chemistry. However, we use techniques of modern biochemistry, biophysics, and cellular/molecular biology to evaluate the biological activities of the compounds we synthesize.

@DanHarki on Twitter